A comparison of 1 Hz rTMS over the medial frontal cortex and 10 Hz rTMS over the dorsolateral prefrontal cortex was completed in healthy smokers. Results showed that 10 Hz rTMS reduced cigarette consumption more than 1 Hz rTMS as well as sham TMS. 10 Hz treatment increased brain activity in the lateral prefrontal cortex and decreased brain activity in the medial frontal cortex. The study demonstrates that 10 Hz rTMS stimulation of the dorsolateral prefrontal cortex in an executive control circuit may be better for developing brain stimulation treatment than 1Hz rTMS of the medial orbitofrontal cortex in a medial reward circuit.
Learning Objectives:
Learners will be able to:
Describe repetitive magnetic stimulation (rTMS) effects on addiction circuits and identify a more effective rTMS treatment protocol (1 Hz over medial frontal cortex vs. 10 Hz over lateral frontal cortex) for smoking cessation.
Describe advancements in non-invasive brain stimulation for smoking cessation.
